Falcao gave the hosts a first-half lead before scoring two goals in the last six minutes as the Porto forwards gave their Russian opponents a torrid time.  

Silvestre Varela also scored for Porto, while Dmitri Kombarov put through his own net. Kombarov atoned by pulling one back for the visitors but Spartak's hopes are all but extinguished with this defeat.  

The good news for the Iberian teams kept on coming as Benfica eased to a 4-1 win over PSV Eindhoven. Javier Saviola rounded off a fine night for the hosts with an injury-time strike after PSV looked to have clawed their back into contention with an 80th-minute goal from Zakaria Labyad.  

See you in the semi-finals? Saviola (right) was among the scorers as Benfica eased to a 4-1 win over PSV

Until Labyad gave PSV hope, Benfica largely dominated with Eduardo Salvio's two strikes either side of half-time adding to Pablo Aimar's opener. 

And Braga made it three Portuguese teams in the driving seat to reach the semi-finals as they posted a valuable 1-1 draw in the away leg of their tie at 10-man Dynamo Kiev.  

Dynamo went after only six minutes through Andriy Yarmolenko but their lead did not last long as Ognjen Vukojevic put through his own net eight minutes later.  

Half-time substitute Andriy Shevchenko was dismissed for the home side after 61 minutes for collecting his second booking.

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